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2055050-87-6

2055050-87-6 structure
2055050-87-6 structure
  • Name: LAU159
  • Chemical Name: LAU159
  • CAS Number: 2055050-87-6
  • Molecular Formula: C17H12ClN3O2
  • Molecular Weight: 325.749
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel GABA Receptor
  • Create Date: 2019-09-09 17:23:50
  • Modify Date: 2025-09-21 11:21:40
  • LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].

Name LAU159
Synonyms 8-Chloro-2-(3-methoxyphenyl)-2,5-dihydro-3H-pyrazolo[4,3-c]quinolin-3-one
Description LAU159 is a functionally selective positive modulator of α1β3 GABA(A) receptor with an EC50 of 2.2 μM[1].
Related Catalog
Target

EC50: 2.2 μM (α1β3 GABA(A) receptor)[1]

References

[1]. Varagic Z, et al. Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface. Br J Pharmacol. 2013 May;169(2):371-83.

Density 1.5±0.1 g/cm3
Boiling Point 473.8±55.0 °C at 760 mmHg
Molecular Formula C17H12ClN3O2
Molecular Weight 325.749
Flash Point 240.3±31.5 °C
Exact Mass 325.061798
LogP 3.16
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.706
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