Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MT-3014
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
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1332727-40-8

1332727-40-8 structure

1332727-40-8 structure

Name: MT-3014
Chemical Name: MT-3014
CAS Number: 1332727-40-8
Molecular Formula: C₂₃H₂₅F₂N₇O
Molecular Weight: 453.49
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2019-08-04 15:40:58
Modify Date: 2024-01-10 15:34:57
MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1].

Name	MT-3014

Description	MT-3014 is a potent, highly selective and brain-penetrated phosphodiesterase 10A (PDE 10A) inhibitor, with IC50s of 0.062 nM and 0.09 nM for human PDE 10A and bovine PDE 10A, respectively[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Neurological Disease
Target	human PDE 10A:0.062 nM (IC50) bovine PDE 10A:0.09 nM (IC50)
References	[1]. Koizumi Y, et al. Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety. Bioorg Med Chem. 2019 Jun 19.

Molecular Formula	C₂₃H₂₅F₂N₇O
Molecular Weight	453.49