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1610802-47-5

1610802-47-5 structure
1610802-47-5 structure
  • Name: LY 3130481
  • Chemical Name: LY3130481
  • CAS Number: 1610802-47-5
  • Molecular Formula: C19H18N4O3S
  • Molecular Weight: 382.44
  • Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
  • Create Date: 2019-08-03 18:20:59
  • Modify Date: 2024-01-30 11:59:47
  • LY3130481 is an AMPA receptor antagonist that is dependent upon transmembrane AMPA receptor regulatory protein (TARP) γ-8, selective inhibits AMPA/TARP γ-8 with an IC50 of 65 nM[1].

Name LY3130481
Description LY3130481 is an AMPA receptor antagonist that is dependent upon transmembrane AMPA receptor regulatory protein (TARP) γ-8, selective inhibits AMPA/TARP γ-8 with an IC50 of 65 nM[1].
Related Catalog
Target

IC50:65 nM (AMPA/TARP γ-8)[1]

References

[1]. Gardinier KM,et al. Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8. J Med Chem. 2016 May 26;59(10):4753-68.

Molecular Formula C19H18N4O3S
Molecular Weight 382.44