2248702-80-7

2248702-80-7 structure

2248702-80-7 structure

Name: TDP1 Inhibitor-1
Chemical Name: TDP1 Inhibitor-1
CAS Number: 2248702-80-7
Molecular Formula: C₂₆H₂₆N₂O₅
Molecular Weight: 446.50
Catalog: Research Areas Cancer
Create Date: 2019-06-29 22:02:33
Modify Date: 2024-01-10 18:53:52
TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].

Name	TDP1 Inhibitor-1

Description	TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 7 μM (Tyrosyl-DNA Phosphodiesterase 1)[1]
References	[1]. Zhang XR, et al. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents. J Med Chem. 2018 Nov 21;61(22):9908-9930.

Molecular Formula	C₂₆H₂₆N₂O₅
Molecular Weight	446.50