2254409-25-9

2254409-25-9 structure
2254409-25-9 structure
  • Name: ALK2-IN-2
  • Chemical Name: ALK2-IN-2
  • CAS Number: 2254409-25-9
  • Molecular Formula: C28H27N5O2S
  • Molecular Weight: 497.61
  • Catalog: Research Areas Cancer
  • Create Date: 2019-06-30 18:34:15
  • Modify Date: 2024-04-05 14:45:48
  • ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].

Name ALK2-IN-2
Description ALK2-IN-2 is a potent and selective inhibitor of activin receptor-like kinase 2 (ALK2) with an IC50 of 9 nM, and over 700-fold selectivity against ALK3[1].
Related Catalog
Target

ALK2:9 nM (IC50)

References

[1]. Jiang JK, et al. Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors. Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362.

Molecular Formula C28H27N5O2S
Molecular Weight 497.61
Hazard Codes Xi
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