1315378-73-4
1315378-73-4 structure
- Name: PDZ1 Domain inhibitor peptide
- Chemical Name: PDZ1 Domain inhibitor peptide
- CAS Number: 1315378-73-4
- Molecular Formula: C38H61N9O11
- Molecular Weight: 819.945
- Catalog: Research Areas Neurological Disease
- Create Date: 2019-06-16 20:06:29
- Modify Date: 2025-08-27 19:35:53
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PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain[1].
| Name | PDZ1 Domain inhibitor peptide |
|---|---|
| Synonyms |
L-Valine, N-[[(2S,5S,14S)-14-[[(2S)-6-amino-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxohexyl]amino]-2-(1-hydroxyethyl)-3,8,15-trioxo-1,4,9-triazacyclopentadec-5-yl]carbonyl]-L-alanyl-
N-({(2S,5S,14S)-2-(1-Hydroxyethyl)-3,8,15-trioxo-14-[(L-tyrosyl-L-lysyl)amino]-1,4,9-triazacyclopentadecan-5-yl}carbonyl)-L-alanyl-L-valine |
| Description | PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 1304.2±65.0 °C at 760 mmHg |
| Molecular Formula | C38H61N9O11 |
| Molecular Weight | 819.945 |
| Flash Point | 742.5±34.3 °C |
| Exact Mass | 819.449036 |
| LogP | -2.24 |
| Appearance | White lyophilised solid |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.597 |
| Storage condition | Desiccate at -20°C |
| Water Solubility | Soluble to 1 mg/ml in 5% acetonitrile / H2O and to 4 mg/ml in DMSO |