1848242-58-9
1848242-58-9 structure
- Name: PI3K/mTOR Inhibitor-2
- Chemical Name: PI3K/mTOR Inhibitor-2
- CAS Number: 1848242-58-9
- Molecular Formula: C20H13ClF2N4O4S
- Molecular Weight: 478.86
- Catalog: Signaling Pathways PI3K/Akt/mTOR mTOR
- Create Date: 2019-03-03 10:44:04
- Modify Date: 2025-08-25 13:29:15
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PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR[1]. Antitumor activity[1].
| Name | PI3K/mTOR Inhibitor-2 |
|---|
| Description | PI3K/mTOR Inhibitor-2 is a potent dual pan-PI3K/mTOR inhibitor with IC50s of 3.4/34/16/1 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ and 4.7 nM for mTOR[1]. Antitumor activity[1]. |
|---|---|
| Related Catalog | |
| Target |
PI3Kα:3.4 nM (IC50) PI3Kβ:34 nM (IC50) PI3Kδ:16 nM (IC50) PI3Kγ:1 nM (IC50) mTOR:4.7 nM (IC50) |
| In Vitro | PI3K/mTOR Inhibitor-2 (Compound 31) inhibits p-AKT and p-p70s6k in MCF-7 cells with IC50s of 11.6 and 89.2 nM, respectively[1]. |
| References |
| Molecular Formula | C20H13ClF2N4O4S |
|---|---|
| Molecular Weight | 478.86 |