851881-59-9
851881-59-9 structure
- Name: (R)-ADX-47273
- Chemical Name: (R)-ADX-47273
- CAS Number: 851881-59-9
- Molecular Formula: C20H17F2N3O2
- Molecular Weight: 369.36
- Catalog: Research Areas Neurological Disease
- Create Date: 2018-09-30 17:42:44
- Modify Date: 2025-09-21 23:52:51
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(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation .
| Name | (R)-ADX-47273 |
|---|
| Description | (R)-ADX-47273 is a potent mGluR5 positive allosteric modulator, with an EC50 of 168 nM for potentiation . |
|---|---|
| Related Catalog | |
| Target |
mGluR5:168 nM (EC50) |
| In Vitro | (R)-ADX-47273 (ADX-47273 (5)) is a potent mGluR5 positive allosteric modulator with an EC50 for potentiation of 168 nM and a 9-fold shift of the glutamate response curve at 1 μM[1]. |
| References |
| Molecular Formula | C20H17F2N3O2 |
|---|---|
| Molecular Weight | 369.36 |