1174985-59-1

1174985-59-1 structure

1174985-59-1 structure

Name: ORL1 antagonist 1
Chemical Name: ORL1 antagonist 1
CAS Number: 1174985-59-1
Molecular Formula: C₂₀H₂₂ClN₅
Molecular Weight: 367.88
Catalog: Signaling Pathways GPCR/G Protein Opioid Receptor
Create Date: 2018-09-05 22:58:19
Modify Date: 2024-01-04 11:35:54
ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM.

Name	ORL1 antagonist 1

Description	ORL1 antagonist 1 is an opioid receptor-like 1 (ORL1) antagonist with an IC50 of 61 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Metabolic Disease Research Areas >> Neurological Disease
Target	IC50: 61 nM (ORL1)[1]
In Vitro	ORL1 antagonist 1 is compound 17[1].
References	[1]. Kobayashi K, et al. Discovery of novel arylpyrazole series as potent and selective opioid receptor-like 1 (ORL1) antagonists. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3627-31.

Molecular Formula	C₂₀H₂₂ClN₅
Molecular Weight	367.88