877239-08-2

877239-08-2 structure

Name: Trityl-PEG10-azide
Chemical Name: Trityl-PEG9-Azide
CAS Number: 877239-08-2
Molecular Formula: C₃₉H₅₅N₃O₁₀
Molecular Weight: 725.868
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-06-08 23:13:31
Modify Date: 2024-01-10 18:23:06
Trityl-PEG10-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Trityl-PEG9-Azide
Synonyms	31-Azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23,26,29-decaoxahentriacontane MFCD22683292 2,5,8,11,14,17,20,23,26,29-Decaoxahentriacontane, 31-azido-1,1,1-triphenyl-

Description	Trityl-PEG10-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562