732278-52-3

732278-52-3 structure

Name: AMPA/kainate antagonist-3
Chemical Name: BDZ-g,GYKI 47409,
CAS Number: 732278-52-3
Molecular Formula: C₂₁H₂₁N₅O₂S
Molecular Weight: 407.14
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2018-07-02 15:04:13
Modify Date: 2025-08-27 13:11:14
BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].

Name	BDZ-g,GYKI 47409,
Synonyms	(R)-5-(4-AMINO-3-METHYL-PHENYL)-8-METHYL-7-(5-METHYL-1,3,4-THIADIAZOL-2-YL)-8,9-DIHYDRO-7H-1,3-DIOXOLO[4,5-H][2,3]-BENZODIAZEPINE

Description	BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Wang C, et al. Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci. 2014;5(2):138-147.

Molecular Formula	C₂₁H₂₁N₅O₂S
Molecular Weight	407.14