509-96-6
509-96-6 structure
- Name: Rotenolone
- Chemical Name: 12alpha-HYDROXYROTENONE
- CAS Number: 509-96-6
- Molecular Formula: C23H22O7
- Molecular Weight: 410.417
- Catalog: Research Areas Cancer
- Create Date: 2018-07-19 11:21:01
- Modify Date: 2025-08-27 15:12:10
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Rotenolone is an antiproliferative agent. Rotenolone shows antiproliferative activity against the ovarian cancer A2780, breast cancer BT-549, prostate cancer DU 145, NSCLC NCI-H460, and colon cancer HCC-2998 cell lines, with IC50s of 0.95, 1.6, 2.7, 2.0, and 2.9 μM, respectively[1].
| Name | 12alpha-HYDROXYROTENONE |
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| Synonyms |
Furo[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-6a-hydroxy-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aR,12aR)-
(2R,6aR,12aR)-6a-hydroxy-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one [1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-6a-hydroxy-8,9-dimethoxy-2-(1-methylethenyl)-, (2R,6aR,12aR)- 12a-Hydroxyrotenone (2R,6aR,12aR)-6a-Hydroxy-2-isopropenyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one |
| Description | Rotenolone is an antiproliferative agent. Rotenolone shows antiproliferative activity against the ovarian cancer A2780, breast cancer BT-549, prostate cancer DU 145, NSCLC NCI-H460, and colon cancer HCC-2998 cell lines, with IC50s of 0.95, 1.6, 2.7, 2.0, and 2.9 μM, respectively[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 623.1±55.0 °C at 760 mmHg |
| Molecular Formula | C23H22O7 |
| Molecular Weight | 410.417 |
| Flash Point | 219.2±25.0 °C |
| Exact Mass | 410.136566 |
| LogP | 4.11 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.622 |
| Storage condition | -20°C |
| Hazard Codes | Xn |
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