124137-35-5

124137-35-5 structure

Name: 2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Chemical Name: 4,6-Diamino-2-(-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS Number: 124137-35-5
Molecular Formula: C₁₀H₁₄N₆O₄
Molecular Weight: 282.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-17 03:05:38
Modify Date: 2024-02-01 11:25:51
2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	4,6-Diamino-2-(-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Description	2-β-D-Ribofuranosyl-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₀H₁₄N₆O₄
Molecular Weight	282.26