1221418-42-3
1221418-42-3 structure
- Name: SAR629
- Chemical Name: SAR629
- CAS Number: 1221418-42-3
- Molecular Formula: C20H19F2N5O
- Molecular Weight: 383.39
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-06-21 03:45:55
- Modify Date: 2024-01-11 23:07:24
-
SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2].
| Name | SAR629 |
|---|
| Description | SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | SAR629 is a potent dual inhibitory action on MAGL and fatty acid amide hydrolase (FAAH). SAR629 inhibits rodent monoglyceride lipase (MGL) activity at subnanomolar potencies (IC50 values of 1.1 nM and 219 pM in rat and mouse brain membranes, respectively)[1]. |
| References |
| Molecular Formula | C20H19F2N5O |
|---|---|
| Molecular Weight | 383.39 |
| Hazard Codes | Xi |
|---|