135023-21-1

135023-21-1 structure

Name: N2,2'-O-Dimethylguanosine
Chemical Name: 2'-O-Methyl-N2-methylguanosine
CAS Number: 135023-21-1
Molecular Formula: C₁₂H₁₇N₅O₅
Molecular Weight: 311.29
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-06-04 10:56:03
Modify Date: 2024-02-03 17:47:53
N2,2'-O-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-O-Methyl-N2-methylguanosine
Synonyms	MFCD28343597

Description	N2,2'-O-Dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₂H₁₇N₅O₅
Molecular Weight	311.29

Hazard Codes	Xn