109304-04-3

109304-04-3 structure

Name: 2-Aminopurine-9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
Chemical Name: 2-AMinopurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
CAS Number: 109304-04-3
Molecular Formula: C₁₀H₁₂FN₅O₃
Molecular Weight: 269.23
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-11-12 20:34:26
Modify Date: 2024-01-13 15:37:44
2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-AMinopurine -9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
Synonyms	9-(2-Deoxy-2-fluoro-β-L-arabinofuranosyl)-9H-purin-2-amine 9H-Purin-2-amine, 9-(2-deoxy-2-fluoro-β-L-arabinofuranosyl)-

Description	2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.