20633-84-5
20633-84-5 structure
- Name: Luteolin 7-rutinoside
- Chemical Name: Lonicerin
- CAS Number: 20633-84-5
- Molecular Formula: C27H30O15
- Molecular Weight: 594.518
- Catalog: Research Areas Infection
- Create Date: 2018-07-04 10:06:42
- Modify Date: 2024-01-04 18:29:42
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Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
| Name | Lonicerin |
|---|---|
| Synonyms |
2-(3,4-Dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranoside
4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy- MFCD03792755 |
| Description | Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. |
|---|---|
| Related Catalog | |
| In Vitro | At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages[1]. |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 954.0±65.0 °C at 760 mmHg |
| Melting Point | 192-196 °C |
| Molecular Formula | C27H30O15 |
| Molecular Weight | 594.518 |
| Flash Point | 316.9±27.8 °C |
| Exact Mass | 594.158447 |
| LogP | 1.35 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.747 |
| RIDADR | NONH for all modes of transport |
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