876746-59-7
876746-59-7 structure
- Name: m-PEG3-NHS ester
- Chemical Name: 1-({3-[2-(2-Methoxyethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione
- CAS Number: 876746-59-7
- Molecular Formula: C12H19NO7
- Molecular Weight: 289.282
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-21 19:37:05
- Modify Date: 2024-01-11 15:53:38
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m-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
| Name | 1-({3-[2-(2-Methoxyethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione |
|---|---|
| Synonyms |
2,5-Pyrrolidinedione, 1-[3-[2-(2-methoxyethoxy)ethoxy]-1-oxopropoxy]-
1-({3-[2-(2-Methoxyethoxy)ethoxy]propanoyl}oxy)-2,5-pyrrolidinedione |
| Description | m-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 393.7±50.0 °C at 760 mmHg |
| Molecular Formula | C12H19NO7 |
| Molecular Weight | 289.282 |
| Flash Point | 191.9±30.1 °C |
| Exact Mass | 289.116150 |
| LogP | -2.51 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.491 |
| Hazard Codes | Xi |
|---|