1186195-56-1

1186195-56-1 structure

Name: BU 226 HCl
Chemical Name: 3-(4,5-Dihydro-1H-imidazol-2-yl)isoquinoline hydrochloride (1:1)
CAS Number: 1186195-56-1
Molecular Formula: C₁₂H₁₂ClN₃
Molecular Weight: 233.697
Catalog: Signaling Pathways GPCR/G Protein Imidazoline Receptor
Create Date: 2018-07-03 11:29:03
Modify Date: 2025-08-27 18:57:03
BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1].

Name	3-(4,5-Dihydro-1H-imidazol-2-yl)isoquinoline hydrochloride (1:1)
Synonyms	3-(4,5-Dihydro-1H-imidazol-2-yl)isoquinoline hydrochloride (1:1) Isoquinoline, 3-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)

Description	BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Imidazoline Receptor Signaling Pathways >> GPCR/G Protein >> Imidazoline Receptor Research Areas >> Neurological Disease
Target	Ki: 1.4 nM (I2)[1] IC50: 534.5 nM (I1)[1]
References	[1]. Hudson AL, et al. Novel selective compounds for the investigation of imidazoline receptors. Ann N Y Acad Sci. 1999 Jun 21;881:81-91.