206552-86-5

206552-86-5 structure

Name: 2′-O-2-Propyn-1-ylguanosine
Chemical Name: 2'-O-2-Propyn-1-ylguanosine
CAS Number: 206552-86-5
Molecular Formula: C₁₃H₁₅N₅O₅
Molecular Weight: 321.29
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-07-10 17:47:26
Modify Date: 2024-01-11 11:16:49
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

Name	2'-O-2-Propyn-1-ylguanosine
Synonyms	2'-O-2-Propyn-1-ylguanosine Guanosine, 2'-O-2-propyn-1-yl-

Description	2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.