684283-16-7

684283-16-7 structure

Name: PPDA
Chemical Name: (2R,3S)-1-(2-Phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid-(2S,3R)-1-(2-phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid (1:1)
CAS Number: 684283-16-7
Molecular Formula: C₄₂H₃₆N₄O₁₀
Molecular Weight: 756.756
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2018-06-17 14:05:51
Modify Date: 2025-08-22 12:00:32
PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D containing receptors[1].

Name	(2R,3S)-1-(2-Phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid-(2S,3R)-1-(2-phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid (1:1)
Synonyms	2,3-Piperazinedicarboxylic acid, 1-(2-phenanthrenylcarbonyl)-, (2R,3S)-, compd. with (2S,3R)-1-(2-phenanthrenylcarbonyl)-2,3-piperazinedicarboxylic acid (1:1) (2R,3S)-1-(2-Phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid - (2S,3R)-1-(2-phenanthrylcarbonyl)-2,3-piperazinedicarboxylic acid (1:1)

Description	PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to NR2C/NR2D containing receptors[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Kinarsky L, et al. Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamate-binding pocket. J Pharmacol Exp Ther. 2005 Jun;313(3):1066-74.