1257555-79-5

1257555-79-5 structure

Name: CB2R-IN-1
Chemical Name: CB2R-IN-1
CAS Number: 1257555-79-5
Molecular Formula: C₂₃H₂₇F₃N₄O₆S₃
Molecular Weight: 608.67
Catalog: Signaling Pathways GPCR/G Protein Cannabinoid Receptor
Create Date: 2018-01-12 21:37:38
Modify Date: 2025-08-25 19:10:01
CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.

Name	CB2R-IN-1

Description	CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor Research Areas >> Neurological Disease
Target	CB2 Receptor:0.9 nM (Ki)
In Vitro	CB2R-IN-1 (Compound 37) is a potent cannabinoid CB2 receptor ligand (Ki=0.9 nM) with excellent selectivity over the CB1 receptor (Ki=8259.3 nM)[1].
References	[1]. Tong L, et al. Expansion of SAR studies on triaryl bis sulfone cannabinoid CB2 receptor ligands. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6785-9.