848258-31-1

848258-31-1 structure

Name: Pemafibrate racemate
Chemical Name: Pemafibrate racemate
CAS Number: 848258-31-1
Molecular Formula: C₂₈H₃₀N₂O₆
Molecular Weight: 490.55
Catalog: Research Areas Others
Create Date: 2018-06-11 17:23:07
Modify Date: 2024-01-09 16:05:50
Pemafibrate racemate is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively.

Name	Pemafibrate racemate
Synonyms	Pemafibrate (racemate)

Description	Pemafibrate racemate is the racemate of pemafibrate, and activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively.
Related Catalog	Research Areas >> Others
Target	h-PPARα:1 nM (EC50) h-PPARδ:1.7 μM (EC50)
In Vitro	Pemafibrate racemate activates PPARα activity, with EC50s of 1 nM, >10 μM and 1.7 μM for h-PPARα, h-PPARγ and h-PPARδ, respectively[1].
References	[1]. Yamazaki Y, et al. Design and synthesis of highly potent and selective human peroxisome proliferator-activated receptor alpha agonists. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4689-93. Epub2007 May 24.