108212-76-6

108212-76-6 structure

Name: N-Acetyl-Calicheamicin
Chemical Name: N-Acetyl-Calicheamicin
CAS Number: 108212-76-6
Molecular Formula: C₅₇H₇₆IN₃O₂₂S₄
Molecular Weight: 1410.39
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-02-03 01:27:43
Modify Date: 2024-01-03 18:41:39
N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: AntibacterialN-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.

Name	N-Acetyl-Calicheamicin

Description	N-Acetyl-Calicheamicin is a potent enediyne antitumor antibiotic. Target: AntibacterialN-Acetyl-Calicheamicin is a a derivative of Calicheamicin. Calicheamicin is a naturally occurring hydrophobic enediyne antibiotic that was isolated from the actinomycete Micromonospora echinospora calichensis. Calicheamicin can interfere with biological processes not simply by cleaving free DNA but also by displacing a DNA-binding protein through competition or modulation of DNA structure.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Cancer
References	[1]. Stasi R, et al. Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia. Cancer Treat Rev. 2008 Feb;34(1):49-60.