Top Suppliers:I want be here
Related CAS#:
101462-82-2 90954-53-3
624735-23-5 1816258-60-2
124756-98-5 196413-73-7
125448-83-1 95210-75-6
102029-74-3 61214-51-5
2877671-74-2 2877629-72-4
2877629-77-9 2877631-12-2
2228463-38-3 2168410-12-4
2229190-79-6 2166739-91-7
124676-45-5 2228329-11-9

101462-82-2

101462-82-2 structure
101462-82-2 structure
  • Name: β-CGRP (human)
  • Chemical Name: β-CGRP, human
  • CAS Number: 101462-82-2
  • Molecular Formula: C162H267N51O48S3
  • Molecular Weight: 3793.41
  • Catalog: Peptides
  • Create Date: 2018-03-21 16:41:28
  • Modify Date: 2025-08-25 17:34:56
  • β-CGRP, human is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells.
Name β-CGRP, human
Description β-CGRP, human is one of calcitonin peptides, acts via the complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP2 in cells.
Related Catalog
Target

IC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay)[1]

In Vitro β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 nM in NG108-15 and HEK293T cells expressing CRLR and RAMP2[1]. CGRP is a potent vasodilator and also shows pro- and -anti-inflammatory activity[2].
References

[1]. McLatchie LM, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998 May 28;393(6683):333-9.

[2]. Russell FA, et al. Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 2014 Oct;94(4):1099-142.
Molecular Formula C162H267N51O48S3
Molecular Weight 3793.41
Storage condition −20°C
WGK Germany 3
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:101462-82-2 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 101462-82-2 | Chemsrc address: https://www.chemsrc.com/en/baike/1470515.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved