1219802-64-8

1219802-64-8 structure
1219802-64-8 structure
  • Name: 2-Iodoacetamide-d4
  • Chemical Name: IODOACETAMIDE-D4
  • CAS Number: 1219802-64-8
  • Molecular Formula: C2D4INO
  • Molecular Weight: 188.99
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA Alkylator/Crosslinker
  • Create Date: 2018-05-21 08:00:00
  • Modify Date: 2024-01-08 16:52:01
  • 2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].

Name IODOACETAMIDE-D4
Description 2-Iodoacetamide-d4 is the deuterium labeled 2-Iodoacetamide[1]. 2-Iodoacetamide (Iodoacetamide), an alkylating agent, is a commonly used agent for alkylation of cysteine during sample preparation for proteomics[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Peter G Hains, et al. The Impact of Commonly Used Alkylating Agents on Artifactual Peptide Modification. J Proteome Resq. 2017 Sep 1;16(9):3443-3447.  

[3]. J J LALICH. Iodoacetamide induced gastric ulcers in rats. Proc Soc Exp Biol Med. 1962 Apr109:905-8.  

Molecular Formula C2D4INO
Molecular Weight 188.99