1000999-96-1

1000999-96-1 structure

Name: Icapamespib
Chemical Name: PU-HZ151
CAS Number: 1000999-96-1
Molecular Formula: C₁₉H₂₃IN₆O₂S
Molecular Weight: 526.39
Catalog: Signaling Pathways Cell Cycle/DNA Damage HSP
Create Date: 2018-06-29 16:39:59
Modify Date: 2025-09-04 19:32:08
Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM. Icapamespib is able to cross blood-brain barrier[1].

Name	PU-HZ151

Description	Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM. Icapamespib is able to cross blood-brain barrier[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HSP Signaling Pathways >> Cell Cycle/DNA Damage >> HSP Research Areas >> Neurological Disease
References	[1]. Bolaender A, et al. Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nat Commun. 2021;12(1):4669. Published 2021 Aug 3.