29106-36-3

29106-36-3 structure

Name: Pinoresinol dimethyl ether
Chemical Name: (7S,7’S,8R,8’R)-eudesmin
CAS Number: 29106-36-3
Molecular Formula: C₂₂H₂₆O₆
Molecular Weight: 386.438
Catalog: Research Areas Neurological Disease
Create Date: 2018-10-17 15:53:58
Modify Date: 2024-01-09 17:20:35
Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from the stem bark of Magnolia kobus with neuritogenic activity. Pinoresinol dimethyl ether ((+)-Eudesmin) can induce neuritis outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways[1][2].

Name	(7S,7’S,8R,8’R)-eudesmin
Synonyms	(1S,3aR,4S,6aR)-1,4-Bis(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan 1H,3H-Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxyphenyl)tetrahydro-, (1S,3aR,4S,6aR)- (7S,7’S,8R,8’R)-eudesmin (1S,3aR,4S,6aR)-1,4-bis(3,4-dimethoxyphenyl)-hexahydrofuro[3,4-c]furan Pinoresinol dimethyl ether

Description	Pinoresinol dimethyl ether ((+)-Eudesmin) is a non-phenolic furofuran lignan isolated from the stem bark of Magnolia kobus with neuritogenic activity. Pinoresinol dimethyl ether ((+)-Eudesmin) can induce neuritis outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. TeruhisaMiyauchi, et al. Formation of (+)-eudesmin in Magnolia kobus DC. Var. borealis sarg. Phytochemistry, 1998, 47(4): 665-670. [2]. Yang YJ, et al. Effects of (+)-eudesmin from the stem bark of magnolia kobus DC. var. borealis Sarg. on neurite outgrowth in PC12 cells. Arch Pharm Res. 2006 Dec;29(12):1114-8.