- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
- Price: ￥328.0/1g ￥1968.0/5g
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- Chengdu Pukang Biotechnology Co., Ltd.
- China
- Product Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
- Price: ￥Inquiry/10g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Lihua Yang
- Email: sales@pu-kang.com
- DC Chemicals Limited
- China
- Product Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-Maleimidobutyric acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
57078-98-5
57078-98-5 structure
- Name: 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
- Chemical Name: 4-Maleimidobutyric Acid
- CAS Number: 57078-98-5
- Molecular Formula: C8H9NO4
- Molecular Weight: 183.161
- Catalog: Chemical reagent Organic reagent Aromatic acid
- Create Date: 2018-09-14 11:27:58
- Modify Date: 2025-08-26 16:30:01
-
4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 4-Maleimidobutyric Acid |
|---|---|
| Synonyms |
1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo-
4-(2,5-dioxopyrrol-1-yl)butanoic acid 4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid MFCD00043139 4-(2,5-Dioxo-2,5-dihydro-pyrrol-1-yl)-butyric acid |
| Description | 4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 400.1±28.0 °C at 760 mmHg |
| Melting Point | 95-98ºC |
| Molecular Formula | C8H9NO4 |
| Molecular Weight | 183.161 |
| Flash Point | 195.8±24.0 °C |
| Exact Mass | 183.053162 |
| PSA | 74.68000 |
| LogP | 0.40 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.553 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Risk Phrases | R36/37/38 |
| Safety Phrases | 26-36 |
| WGK Germany | 3 |