215176-58-2

215176-58-2 structure

Name: 3'-Azido-3'-deoxy-5-Methyuridine
Chemical Name: zidovudine
CAS Number: 215176-58-2
Molecular Formula: C₁₀H₁₃N₅O₅
Molecular Weight: 283.24
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-05-17 10:40:13
Modify Date: 2024-01-21 11:35:59
3’-Azido-3’-deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	zidovudine
Synonyms	1-((2R,3R,4S,5S)-4-Azido-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione 3'-azido-3'-deoxy-5-methyluridine 3'-azido-3'-deoxythymidine 1-(3'-azido-3'-deoxy-β-D-ribofuranosyl)thymine 1-(3-azido-3-deoxy-β-D-ribofuranosyl)thymine AZT 3'-azido-3'-deoxy-β-ribosylthimine

Description	3’-Azido-3’-deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.