147214-63-9

147214-63-9 structure

Name: cyclothialidine
Chemical Name: cyclothialidine
CAS Number: 147214-63-9
Molecular Formula: C₂₆H₃₅N₅O₁₂S
Molecular Weight: 641.64700
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-16 09:33:59
Modify Date: 2025-08-27 06:11:23
Cyclothialidine ( Ro 09-1437) is a potent DNA gyrase inhibitor isolated from Streptomyces filipinensisNR0484[1].

Name	cyclothialidine
Synonyms	N-[[(4R,7S)-1,3,4,5,6,7,8,10-octahydro-12,14-dihydroxy-7-[[(3R)-3-hydroxy-1-L-seryl-L-prolyl]amino]-11-methyl-6,10-dioxo-9,2,5-benzoxathiaazacyclododecin-4-yl]carbonyl]-L-alanine Cyclothialidine

Description	Cyclothialidine ( Ro 09-1437) is a potent DNA gyrase inhibitor isolated from Streptomyces filipinensisNR0484[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Angehrn P, et al. New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. J Med Chem. 2004;47(6):1487-1513.