57906-85-1

57906-85-1 structure

Name: Corynoxidine
Chemical Name: (-)-corynoxidine
CAS Number: 57906-85-1
Molecular Formula: C₂₁H₂₅NO₅
Molecular Weight: 371.42700
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-05-06 19:56:02
Modify Date: 2024-01-14 12:04:52
(-)-Corynoxidine is an acetylcholinesterase inhibitor with an IC50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa[1].(-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees[2].

Name	(-)-corynoxidine
Synonyms	(7S,13aS)-2,3,9,10-Tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquino[3,2-a]isoquinoline 7-oxide Corynoxidin corynoxidine

Description	(-)-Corynoxidine is an acetylcholinesterase inhibitor with an IC50 value of 89.0 μM, isolated from the aerial parts of Corydalis speciosa[1].(-)-Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Neuronal Signaling >> AChE Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 89.0 μM (acetylcholinesterase)[1]
References	[1]. Kim DK, et al. Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. Arch Pharm Res. 2004 Nov;27(11):1127-31. [2]. Yang DL, et al. A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera. J Asian Nat Prod Res. 2013;15(3):315-8.