6741-73-7

6741-73-7 structure

Name: 1-(4-thio-beta-D-ribofuranosyl)uracil
Chemical Name: 1-(4-thio-β-D-ribofuranosyl)uracil
CAS Number: 6741-73-7
Molecular Formula: C₉H₁₂N₂O₅S
Molecular Weight: 260.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-02-05 00:52:57
Modify Date: 2024-01-05 08:52:09
4′-Thiouridine (1-(4-thio-beta-D-ribofuranosyl)uracil) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	1-(4-thio-β-D-ribofuranosyl)uracil
Synonyms	1-<4-Thio-α-ribofuranosyl>-uracil 1-(4-thio-β-d-ribofuranosyl)uracil 1-(4-thio-β-D-ribofuransoyl)uracil 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidine-2,4-dione 4'-thio-uridine

Description	4′-Thiouridine (1-(4-thio-beta-D-ribofuranosyl)uracil) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.