22048-97-1

22048-97-1 structure

Name: lepomerine
Chemical Name: leptomerine
CAS Number: 22048-97-1
Molecular Formula: C₁₃H₁₅NO
Molecular Weight: 201.26400
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2018-03-26 13:06:11
Modify Date: 2025-08-23 11:15:12
Leptomerine, an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer Disease. Leptomerine inhibits acetyl cholinesterase (AChE) with an IC50 of 2.5 μM. Anticholinesterasic activity[1].

Name	leptomerine
Synonyms	1-Methyl-2-propyl-1H-chinolon-4 1-Methyl-2-propyl-1H-quinolin-4-one 1-methyl-2-propyl-1H-quinolin-4-one

Description	Leptomerine, an alkaloid from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer Disease. Leptomerine inhibits acetyl cholinesterase (AChE) with an IC50 of 2.5 μM. Anticholinesterasic activity[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Cardoso-Lopes EM, et al. Alkaloids from stems of Esenbeckia leiocarpa Engl. (Rutaceae) as potential treatment for Alzheimer disease. Molecules. 2010 Dec 13;15(12):9205-13.