1415407-60-1
1415407-60-1 structure
- Name: TC-G 1005
- Chemical Name: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
- CAS Number: 1415407-60-1
- Molecular Formula: C25H25N3O2
- Molecular Weight: 399.48500
- Create Date: 2018-06-10 11:45:18
- Modify Date: 2023-01-17 17:57:41
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TC-G 1005 is a potent, selective and orally active agonist of the BA receptor Takeda G protein-coupled receptor 5 (TGR5), with EC50s of 0.72 and 6.2 nM for hTGR5 and mTGR5, respectively. TC-G 1005 can reduce glucose levels in vivo.
| Name | (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
|---|---|
| Synonyms |
Methanone, (4-cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]-
(4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 564.5±50.0 °C at 760 mmHg |
| Molecular Formula | C25H25N3O2 |
| Molecular Weight | 399.48500 |
| Flash Point | 295.2±30.1 °C |
| Exact Mass | 399.19500 |
| PSA | 45.67000 |
| LogP | 4.44 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.653 |
| Storage condition | -20°C |