1415407-60-1

• 常用中文名：TC-G 1005,GPBA受体(TGR5)激动剂
• 常用英文名：TC-G 1005
• CAS号：1415407-60-1
• 分子式：C₂₅H₂₅N₃O₂
• 分子量：399.48500
• 发布时间：2018-06-10 11:45:18
• 更新时间：2025-08-26 02:11:10
• TC-G 1005 is a potent, selective and orally active agonist of the BA receptor Takeda G protein-coupled receptor 5 (TGR5), with EC50s of 0.72 and 6.2 nM for hTGR5 and mTGR5, respectively. TC-G 1005 can reduce glucose levels in vivo.

名称

• 中文名: TC-G 1005,GPBA受体(TGR5)激动剂
• 英文名: (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone
• 英文别名: Methanone, (4-cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]-; (4-Cyclopropyl-3,4-dihydro-1(2H)-quinoxalinyl)[4-(2,5-dimethylphenoxy)-3-pyridinyl]methanone

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 564.5±50.0 °C at 760 mmHg
• 分子式: C₂₅H₂₅N₃O₂
• 分子量: 399.48500
• 闪点: 295.2±30.1 °C
• 精确质量: 399.19500
• PSA: 45.67000
• LogP: 4.44
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.653
• 储存条件: -20°C