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China
Product Name: Midazolam maleate
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59467-94-6

59467-94-6 structure

59467-94-6 structure

Name: midazolam maleate
Chemical Name: (Z)-but-2-enedioic acid,8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS Number: 59467-94-6
Molecular Formula: C₂₂H₁₇ClFN₃O₄
Molecular Weight: 441.840
Catalog: API Nervous system medication Other nervous system medication
Create Date: 2018-02-07 08:00:00
Modify Date: 2025-08-23 18:36:00

Name	(Z)-but-2-enedioic acid,8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
Synonyms	8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo(1,5-a)(1,4)benzodiazepine monomaleate Midazolam maleate salt Dormicum midazolam maleate Ro 21-3981/001 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluorophenyl)-1-methyl-, (2Z)-2-butenedioate (1:1) 4H-Imidazo[1,5-a][1,4]benzodiazepine, 8-chloro-6-(2-fluoro-phenyl)-1-methyl-, (Z)-2-butenedioate MFCD00941440 EINECS 261-775-0 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine (2Z)-2-butenedioate (1:1) Ro-21-3981/001 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine monomaleate 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine (2Z)-but-2-enedioate (1:1) Dormicum maleate Hypnovel 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine maleate salt

Boiling Point	496.9ºC at 760 mmHg
Molecular Formula	C₂₂H₁₇ClFN₃O₄
Molecular Weight	441.840
Exact Mass	441.089172
PSA	104.78000
LogP	3.47160
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI2922200

CAS REGISTRY NUMBER :: 59467-94-6

LAST UPDATED :: 199707

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C18-H13-Cl-F-N3.C4-H4-O4

MOLECULAR WEIGHT :: 441.87

WISWESSER LINE NOTATION :: T B576 BN DN HN GHJ C1 IR BF& LG &QV1U1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 31,2180,1981

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 86 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 31,2180,1981

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	UN 3249
WGK Germany	3
RTECS	NI2922200
Packaging Group	III
Hazard Class	6.1(b)

Precursor 3
110-16-7 59467-70-8 59468-44-9
DownStream 0

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