1228765-67-0

1228765-67-0 structure

Name: Edaravone D5
Chemical Name: 1-(d5-phenyl)-3-methyl-1H-pyrazol-5(4H)-one
CAS Number: 1228765-67-0
Molecular Formula: C₁₀H₅D₅N₂O
Molecular Weight: 179.23000
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-06-11 22:40:09
Modify Date: 2024-01-07 18:27:29
Edaravone D5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].

Name	1-(d5-phenyl)-3-methyl-1H-pyrazol-5(4H)-one
Synonyms	edaravone d5

Description	Edaravone D5 is a deuterium labeled Edaravone. Edaravone is a strong novel free radical scavenger, and inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator[1][2][3][4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Metabolic Enzyme/Protease >> MMP Research Areas >> Neurological Disease
References	[1]. Yoshida, H., et al. Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury. CNS Drug Rev, 2006. 12(1): p. 9-20. [2]. Okamura, K., et al. Edaravone, a free radical scavenger, attenuates cerebral infarction and hemorrhagic infarction in rats with hyperglycemia. Neurol Res, 2013. [3]. Garcia CA, et al. Edaravone reduces astrogliosis and apoptosis in young rats with kaolin-induced hydrocephalus. Childs Nerv Syst. 2016 Dec 17. [Epub ahead of print] [4]. Bai X, et al. Protective Effect of Edaravone on Glutamate-Induced Neurotoxicity in Spiral Ganglion Neurons. Neural Plast. 2016;2016:4034218. Epub 2016 Nov 10.