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882-09-7

882-09-7 structure
882-09-7 structure
Name clofibric acid
Synonyms Clofibrin
Regulipid
a-(p-Chlorophenoxy)isobutyric Acid
2-(p-chlorophenoxy)-isobutyric acid
PCIB
4-CPIB
2-(4-Chlorophenoxy)-2-methylpropanoic acid
Clofibric
2-(4-chlorophenoxy)isobutyric acid
Chlorofibrinic acid
Arteriohom
PCPIB
Clofibric acid
Chlorfibrinic acid
EINECS 212-925-9
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-
MFCD00004192
4-Chlorophenoxy-iso-butyric Acid
2-(p-Chlorophenoxy)-2-methylpropionic Acid
2-(4-Chlorophenoxy)-2-methylpropionic acid
Clofibric acid [DCF:INN]
Clofibrinic acid
Regadrin
Description Clofibric acid is a plant growth regulator against the plant hormone auxin.
Related Catalog
Density 1.3±0.1 g/cm3
Boiling Point 324.1±17.0 °C at 760 mmHg
Melting Point 120-122 °C(lit.)
Molecular Formula C10H11ClO3
Molecular Weight 214.645
Flash Point 149.8±20.9 °C
Exact Mass 214.039673
PSA 46.53000
LogP 2.72
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.541
Storage condition Store at RT

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UE9455000
CHEMICAL NAME :
Propionic acid, 2-(p-chlorophenoxy)-2-methyl-
CAS REGISTRY NUMBER :
882-09-7
BEILSTEIN REFERENCE NO. :
1874067
LAST UPDATED :
199612
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C10-H11-Cl-O3
MOLECULAR WEIGHT :
214.66
WISWESSER LINE NOTATION :
QVX1&1&OR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human
DOSE/DURATION :
260 mg/kg/91D
TOXIC EFFECTS :
Liver - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
897 mg/kg
TOXIC EFFECTS :
Liver - other changes
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
727 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1170 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
683 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
219 gm/kg/2Y-C
TOXIC EFFECTS :
Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Metabolism (Intermediary) - lipids including transport
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
17750 mg/kg/10W-C
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Biochemical - Effect on specific coenzyme - CoA

MUTATION DATA

TEST SYSTEM :
Rodent - rat
DOSE/DURATION :
2100 mg/kg/1W (Continuous)
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 12,1557,1991
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;Xi: Irritant;
Risk Phrases R22
Safety Phrases S36-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS UE9455000
HS Code 2918990090
HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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