63409-12-1

63409-12-1 structure

Name: Aivlosin
Chemical Name: Tylvalosin
CAS Number: 63409-12-1
Molecular Formula: C₅₃H₈₇NO₁₉
Molecular Weight: 1042.25
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2017-04-01 11:45:08
Modify Date: 2025-08-22 22:12:21
Tylvalosin (Acetylisovaleryltylo?sin) is a broad-spectrum macrolide antibiotic that has antibacterial activity. Tylvalosin is an antiviral agent and can be used for PRRSV infection. . Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, relieves oxidative stress, and relieves acute lung injury by suppression of NF-κB activation[1][2].

Name	Tylvalosin
Synonyms	O3'-Acetyl-2'-desoxy-adenosin 3'-O-Acetyl-2'-deoxyadenosin 2'-deoxy-3'-O-acetyladenosine O3'-acetyl-2'-deoxy-adenosine 3-O-acetyl-4"-O-isovaleryltylosin 2'-Deoxyadenosine 3'-acetate 3-acetate 4B-(3-methylbutanoate) 3'-O-Acetyl-2'-desoxyadenosin

Description	Tylvalosin (Acetylisovaleryltylo?sin) is a broad-spectrum macrolide antibiotic that has antibacterial activity. Tylvalosin is an antiviral agent and can be used for PRRSV infection. . Tylvalosin induces apoptosis. Tylvalosin also has anti-inflammatory activity, relieves oxidative stress, and relieves acute lung injury by suppression of NF-κB activation[1][2].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Albert Philip Adrian Mockett, et al. Use of tylvalosin as antiviral agent. Patent. WO2008007104. [2]. Zhao Z, et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. Biochem Pharmacol. 2014 Jul 1;90(1):73-87. [3]. Moges R, et al. Anti-Inflammatory Benefits of Antibiotics: Tylvalosin Induces Apoptosis of Porcine Neutrophils and Macrophages, Promotes Efferocytosis, and Inhibits Pro-Inflammatory CXCL-8, IL1α, and LTB4 Production, While Inducing the Release of Pro-Resolving Lipoxin A4 and Resolvin D1. Front Vet Sci. 2018 Apr 11;5:57.

122825-66-5

~52%

63409-12-1

122825-66-5

~45%