e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Organic letters

A Highly Selective Synthesis of Dialkenyl Sulfones via Cross-Metathesis of Divinyl Sulfone

M Bieniek, D Koloda, K Grela

Index: Fishman, Andrew G.; Mallams, Alan K.; Rossman, Randall R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 787 - 798

Full Text: HTML

Citation Number: 15

Abstract

... All Publications/Website. Select a Journal or Book. ... 19 In some cases, we also observed the formation of smaller amounts of the undesired disubstituted products 8 (9−31%). In the case of 8b,e−g and 8i we were able to isolate and fully characterize them. ... entry, 6b−i, R, cat. ...

mycinamicin II 3'-N-oxide Structure

mycinamicin II ...

~56%

miporamicin Structure

12,13-Didehydro-14-hydroxy-12,12-O-seco-13-deoxymycinamicin I Structure

12,13-Didehydro...

~%

miporamicin Structure

rosaramicin N-oxide Structure

rosaramicin N-oxide

~69%

rosamicin Structure

12,13-de-epoxy-12,13-didehydrorosamicin 20-dimethyl acetal Structure

12,13-de-epoxy-...

~%

rosamicin Structure

rosaramicin 20-dimethyl acetal 3'-N-oxide Structure

rosaramicin 20-...

~%

rosamicin Structure

2',3,4'''-tri-O-acetyl-4''-O-isovaleryltylosin Structure

2',3,4'''-tri-O...

~52%

Aivlosin Structure

Ethanoic anhydride Structure

Ethanoic anhydride

3-O-acetyl-23-O-demycinosyl-12,13-epoxy-4''-O-isovaleryltylosin Structure

3-O-acetyl-23-O...

~90%

[6-[5-acetyloxy-6-[[(14E)-7-acetyloxy-2-(acetyloxymethyl)-3-ethyl-8,12,16-trimethyl-5,13-dioxo-10-(2-oxoethyl)-4,17-dioxabicyclo[14.1.0]heptadec-14-en-9-yl]oxy]-4-(dimethylamino)-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate Structure

[6-[5-acetyloxy...

rosamicin Structure

~61%

de-epoxy rosamicin Structure

de-epoxy rosamicin

rosamicin Structure

~%

12,13-de-epoxy-12,13-didehydrorosamicin 20-dimethyl acetal Structure

12,13-de-epoxy-...

de-epoxy rosamicin Structure

de-epoxy rosamicin

rosaramicin N-oxide Structure

rosaramicin N-oxide

~%

12,13-de-epoxy-12,13-didehydrorosamicin 20-dimethyl acetal Structure

12,13-de-epoxy-...

de-epoxy rosamicin Structure

de-epoxy rosamicin

12,13-de-epoxy-12,13-didehydrorosamicin 20-dimethyl acetal Structure

12,13-de-epoxy-...

~%

de-epoxy rosamicin Structure

de-epoxy rosamicin

rosaramicin 20-dimethyl acetal 3'-N-oxide Structure

rosaramicin 20-...

~%

de-epoxy rosamicin Structure

de-epoxy rosamicin

rosaramicin N-oxide Structure

rosaramicin N-oxide

~%

de-epoxy rosamicin Structure

de-epoxy rosamicin