95014-75-8

95014-75-8 structure

Name: Phytochelatin 2 (PC2)
Chemical Name: H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B (2))
CAS Number: 95014-75-8
Molecular Formula: C₁₈H₂₉N₅O₁₀S₂
Molecular Weight: 539.58000
Catalog: Research Areas Others
Create Date: 2018-03-18 02:11:56
Modify Date: 2024-01-03 10:41:35
Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis[1][2].

Name	H-γ-L-Glu-L-Cys-γ-L-Glu-L-Cys-Gly-OH (cadystin B (2))
Synonyms	PC2 γGlu-Cys-γGlu-Cys-Gly H-(γ-Glu-Cys)2-Gly-OH H-(γ-Glu-Cys)2-Gly-OH (γ-Glu-Cys)2-Gly Cadystin (γEC)2G

Description	Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal homeostasis[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Phytochelatin synthase (PCS) uses the substrates glutathione (GSH, γGlu-Cys-Gly) and a cadmium (Cd)-bound GSH (Cd∙GS2) to produce the shortest phytochelatin product (PC2, (γGlu-Cys)2-Gly) through a ping-pong mechanism[3]. Phytochelatins and their glutathione (GSH) precursor are thiol-rich peptides that play an important role in heavy metal detoxification in plants and microorganisms[4].
References	[1]. phytochelatin, heavy, metals, chelate, homeostasis, glutathione, microorganisms, toxicity [2]. Dennis KK, et al. Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental metals. Database (Oxford). 2019;2019:baz083. [3]. Chia JC, et al. Tentative identification of the second substrate binding site in Arabidopsis phytochelatin synthase. PLoS One. 2013;8(12):e82675. Published 2013 Dec 5. [4]. Jacquart A, et al. Cd2+ and Pb2+ complexation by glutathione and the phytochelatins. Chem Biol Interact. 2017;267:2-10.