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8025-81-8

8025-81-8 structure
8025-81-8 structure
  • Name: Spiramycin
  • Chemical Name: Spiramycin
  • CAS Number: 8025-81-8
  • Molecular Formula: C43H74N2O14
  • Molecular Weight: 843.053
  • Catalog: API Antibiotics Macrolide drug
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2025-08-20 19:19:16
  • Spiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens.

Name Spiramycin
Synonyms [(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde (non-preferred name)
Leucomycin
Foromacidin
Provamycin
[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-{[(2S,3R,4R,5S,6R)-5-{[(2S,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-10-{[(2R,5S,6S)-5-(dimethylamino)-6-methyltetrahydro-2H-pyran-2-yl]oxy}-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxooxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
Spiramycin I
Rovamycin
Description Spiramycin is a clinically important 16-member macrolide antibiotic produced by Streptomyces ambofaciens.
Related Catalog
Target

Bacterial[1]

References

[1]. Nguyen HC, et al. Post-PKS tailoring steps of the spiramycin macrolactone ring in Streptomyces ambofaciens. Antimicrob Agents Chemother. 2013 Aug;57(8):3836-42.

Density 1.2±0.1 g/cm3
Boiling Point 913.7±65.0 °C at 760 mmHg
Molecular Formula C43H74N2O14
Molecular Weight 843.053
Flash Point 506.4±34.3 °C
Exact Mass 842.513977
LogP 3.06
Vapour Pressure 0.0±0.6 mmHg at 25°C
Index of Refraction 1.550
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26-36-24/25
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS WG9400000
HS Code 29419090
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