9039-53-6

9039-53-6 structure

Name: Urokinase
Chemical Name: Urokinase
CAS Number: 9039-53-6
Molecular Formula: C₂₁H₂₅BrN₂O₃
Molecular Weight:
Catalog: Biochemical Enzymes and coenzymes
Create Date: 2019-01-11 12:35:04
Modify Date: 2024-01-02 08:54:48
Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research[1].

Name	Urokinase
Synonyms	urokinase, high mw (urine) ec 3.4.99.26 urokinase, low mw (urine) urokinase urokinase upa 2-chain urokinase, high molecular weight urokinase 2-chain MFCD00132566 urokinase (mixed)

Description	Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cancer Research Areas >> Cardiovascular Disease
In Vitro	Urokinase peptidolytic(uPA) 在非小细胞肺癌 (NSCLC) 中能够增加 uPAR 蛋白质和 mRNA 水平的表达[1]。
References	[1]. Nunzia Montuori, et al. Urokinase-mediated posttranscriptional regulation of urokinase-receptor expression in non small cell lung carcinoma. Int J Cancer. 2003 Jun 20;105(3):353-60

Molecular Formula	C₂₁H₂₅BrN₂O₃
Appearance	powder \| white
Storage condition	2-8°C
Water Solubility	Soluble in water. \| Reconstitute in water at 100µg/ml

Hazard Codes	B
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	OB8900000