609799-22-6

609799-22-6 structure

Name: Tasimelteon
Chemical Name: tasimelteon
CAS Number: 609799-22-6
Molecular Formula: C₁₅H₁₉NO₂
Molecular Weight: 245.317
Catalog: Signaling Pathways GPCR/G Protein Melatonin Receptor
Create Date: 2018-03-06 08:00:00
Modify Date: 2024-01-10 18:52:16
Tasimelteon is a melatonin MT1 and MT2 receptor agonist.Target: melatonin receptorTasimelteon is a novel circadian regulator, is the first product for the treatment of Non-24-hour Sleep-Wake Disorder (Non-24) approved by either the FDA or the European Medicines Agency (EMA). Tasimelteon is a potent and specific melatonin (MT1 and MT2) receptor agonist with 2 - 4 times greater affinity for the MT2 receptor.

Name	tasimelteon
Synonyms	Hetlioz Tasimelteon MA 1 N-[[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl]propanamide UNII-SHS4PU80D9 Propanamide, N-[[(1R,2R)-2-(2,3-dihydro-4-benzofuranyl)cyclopropyl]methyl]- N-{[(1R,2R)-2-(2,3-Dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide VEC-162

Description	Tasimelteon is a melatonin MT1 and MT2 receptor agonist.Target: melatonin receptorTasimelteon is a novel circadian regulator, is the first product for the treatment of Non-24-hour Sleep-Wake Disorder (Non-24) approved by either the FDA or the European Medicines Agency (EMA). Tasimelteon is a potent and specific melatonin (MT1 and MT2) receptor agonist with 2 - 4 times greater affinity for the MT2 receptor.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Melatonin Receptor Signaling Pathways >> Neuronal Signaling >> Melatonin Receptor Research Areas >> Neurological Disease
References	[1]. Leger D, et al. Safety profile of tasimelteon, a melatonin MT1 and MT2 receptor agonist: pooled safety analyses from six clinical studies. Expert Opin Drug Saf. 2015;14(11):1673-85. [2]. Keating GM, et al. Tasimelteon: A Review in Non-24-Hour Sleep-Wake Disorder in Totally Blind Individuals. CNS Drugs. 2016 Mar 22.