187947-37-1
187947-37-1 structure
- Name: Arachidonoyl serotonin
- Chemical Name: Arachidonoylserotonin
- CAS Number: 187947-37-1
- Molecular Formula: C30H42N2O2
- Molecular Weight: 462.667
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel TRP Channel
- Create Date: 2016-02-18 18:39:08
- Modify Date: 2024-01-02 15:10:04
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N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1].
| Name | Arachidonoylserotonin |
|---|---|
| Synonyms |
(5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-icosatetraenamide
Arachidonoyl serotonin AA-5-HT N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenamide (5Z,8Z,11Z,14Z)-N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]icosa-5,8,11,14-tetraenamide Arachidonyl serotonin,N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-5,8,11,14-eicosatetraenamide 5,8,11,14-Eicosatetraenamide, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-, (5Z,8Z,11Z,14Z)- Arachidonyl serotonin N-Arachidonoylserotonin |
| Description | N-Arachidonoylserotonin (Arachidonyl serotonin; AA-5-HT) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 value of 1~12 µM. N-Arachidonoylserotonin acts also as an antagonist of transient receptor potential vanilloid-type 1 (TRPV1) channels (IC50=70~100 nM). N-Arachidonoylserotonin is analgesic in rodents [1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 1~12 µM (FAAH), 70~100 nM (TRPV1 channels)[1] |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 680.5±55.0 °C at 760 mmHg |
| Molecular Formula | C30H42N2O2 |
| Molecular Weight | 462.667 |
| Flash Point | 365.3±31.5 °C |
| Exact Mass | 462.324615 |
| PSA | 65.12000 |
| LogP | 7.16 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.574 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |