1257-78-9

1257-78-9 structure
1257-78-9 structure
  • Name: prochlorperazine edisylate
  • Chemical Name: prochlorperazine edisylate
  • CAS Number: 1257-78-9
  • Molecular Formula: C22H30ClN3O6S3
  • Molecular Weight: 564.13800
  • Create Date: 2016-10-02 18:39:29
  • Modify Date: 2024-01-31 14:34:22

Name prochlorperazine edisylate
Synonyms 2-CHLORO-10-[3-(4-METHYL-1-PIPERAZINYL)PROPYL]PHENOTHIAZINE 1,2-ETHANEDISULFONATE (1:1)
2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazineedisylate
2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine1,2-ethanedisulfo
PROCHLORPERAZINE ETHANE DISULFONATE
ethane-1,2-disulphonic acid,compound with 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine (1:1)
prochlorperazine edisylate usp
2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazinethanedisulfona
Boiling Point 524.8ºC at 760 mmHg
Molecular Formula C22H30ClN3O6S3
Molecular Weight 564.13800
Flash Point 271.2ºC
Exact Mass 563.09900
PSA 160.52000
LogP 5.44460
Vapour Pressure 4.15E-11mmHg at 25°C
Storage condition 2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SO2975000
CHEMICAL NAME :
Phenothiazine, 2-chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-, ethanedisulfonate
CAS REGISTRY NUMBER :
1257-78-9
LAST UPDATED :
199504
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C20-H24-Cl-N3-S.C2-H6-O6-S2
MOLECULAR WEIGHT :
564.18
WISWESSER LINE NOTATION :
T C666 BN ISJ EG B3- AT6N DNTJ D1 &WSQ2SWQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,40,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
177 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 12,142,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
320 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,40,1972 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
350 mg/kg
SEX/DURATION :
female 7-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4) Reproductive - Effects on Newborn - behavioral
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 205,1220,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3225 No. of Facilities: 70 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 4939 (estimated) No. of Female Employees: 4444 (estimated)
Hazard Codes Xn
Risk Phrases 22
RTECS SO2975000