869898-86-2

869898-86-2 structure

Name: platencin
Chemical Name: Platencin
CAS Number: 869898-86-2
Molecular Formula: C₂₄H₂₇NO₆
Molecular Weight: 425.474
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-21 10:53:30
Modify Date: 2025-08-26 09:21:36
Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively[1].

Name	Platencin
Synonyms	platencin 2,4-Dihydroxy-3-({3-[(1S,5S,6R)-5-methyl-9-methylene-4-oxotricyclo[6.2.2.0]dodec-2-en-5-yl]propanoyl}amino)benzoic acid Benzoic acid, 3-[[3-[(4aS,8S,8aR)-1,3,4,7,8,8a-hexahydro-8-methyl-3-methylene-7-oxo-2H-2,4a-ethanonaphthalen-8-yl]-1-oxopropyl]amino]-2,4-dihydroxy-

Description	Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Wang J, et al. Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7612-6.