129280-33-7

129280-33-7 structure

Name: Semilicoisoflavone B
Chemical Name: semilicoisoflavone B
CAS Number: 129280-33-7
Molecular Formula: C₂₀H₁₆O₆
Molecular Weight: 352.337
Catalog: Natural product Flavonoids
Create Date: 2017-05-07 20:37:23
Modify Date: 2025-08-25 18:54:16
Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].

Name	semilicoisoflavone B
Synonyms	4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)- SemilicoisoflavoneB 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one 5,7,8'-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one Semilicoisoflavone B

Description	Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Gu MY, et al. Glycyrrhiza uralensis and Semilicoisoflavone B Reduce Aβ Secretion by Increasing PPARγ Expression and Inhibiting STAT3 Phosphorylation to Inhibit BACE1 Expression. Mol Nutr Food Res. 2018 Mar;62(6):e1700633.

Hazard Codes	Xi