2863-04-9

2863-04-9 structure

Name: Thymidine 3',5'-disphosphate
Chemical Name: Thymidine 3',5'-diphosphate
CAS Number: 2863-04-9
Molecular Formula: C₁₀H₁₆N₂O₁₁P₂
Molecular Weight: 402.19
Catalog: Research Areas Cancer
Create Date: 2016-08-18 15:47:45
Modify Date: 2024-01-22 12:01:19
Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of SND1 (the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate is an anti-HCC agent and exhibits anti-tumor efficacy in vivo[1].

Name	Thymidine 3',5'-diphosphate
Synonyms	thymidine-3',5'-diphosphate

Description	Thymidine 3',5'-disphosphate (Deoxythymidine 3′,5′-diphosphate; pdTp) is a selective small molecule inhibitor of SND1 (the miRNA regulatory complex RISC subunit) and inhibits SND1 activity. Thymidine 3',5'-disphosphate is an anti-HCC agent and exhibits anti-tumor efficacy in vivo[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: SND1[1]
References	[1]. Nidhi Jariwala, et al. Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma. Cancer Res. 2017 Jun 15;77(12):3306-3316. [2]. Byoung Kwon Yoo, et al. Increased RNA-induced silencing complex (RISC) activity contributes to hepatocellular carcinoma. Hepatology. 2011 May;53(5):1538-48.

Hazard Codes	Xi